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They showed little concern when Homer suffered a heart attack.
While he was undergoing bypass surgery, they tried to set Marge up with a sleazy man named encouraging plaintiff to take an extended leave of absence from the group, during the very time when the group would be recording its song for the Coca-Cola commercial.” So now Kaplan is asking for 0,000 in personal damages.
However, researchers have determined that the underlying defect in types A and B involves mutations in the SMPD1 gene and deficiency of the enzyme acid sphingomyelinase, which does not occur in NPC.
Additional terms have been used in the past to describe NPC including DAF syndrome, juvenile dystonic lipidosis, lipid histiocytosis, and sea blue histiocyte disease.
Patty and Selma have also brought home "souvenirs" from their vacations, including a pillowcase full of seashells from their trip to Sulfur Bay that they forced the family to help them clean and organize.
Niemann-Pick disease type C (NPC) is a rare progressive genetic disorder characterized by an inability of the body to transport cholesterol and other fatty substances (lipids) inside of cells.
This leads to the abnormal accumulation of these substances within various tissues of the body, including brain tissue.
Low levels or inactivity of the alpha-mannosidase enzyme leads to the abnormal accumulation of compounds upstream in the metabolic pathway in the cells of affected individuals with unwanted consequences.
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